Making good use of Logitech V20 Speaker

I brought a Logitech V20 Speaker and so far I am please with the performance. I have issue using it on my home desktop, but I strongly suspected that it's mainly because I have too many USB devices connecting to the desktop. In fact, I used the speaker with 2 of my office machines and then my Lenovo X60T Tablet PC, and none of them had issue. In fact, I even hooked the speaker to my X60T running OSX 10.5.1 and GarageBand 2008 had no problem recognizing and use it to play music.